Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2023

Myanmar   Health   Sciences   Research   Journal

Volume   35,  Number   1-3

TITLE:   Acute Toxicity and Hypoglycemic Activity of Dregea volubilis Benth. Leaves (ေခွးေတာက်) on Animal Model
AUTHOR:   Khine Khine Lwin*, Khin Phyu Phyu, Phyu Phyu Win, Aye win Oo, Nu Nu Win, Myint Myint Khine, San San Myint and Mie Mie Thaw
SOURCE:   Myanmar Health Sciences Research Journal, 2023; 35(1-3):34-41
ABSTRACT:  

Dregea volubilis Benth. is traditionally used for treatment of Diabetes Mellitus in India and Myanmar traditional medicines. This study was performed to determine phytochemical constituents, acute toxicity in mice and hypoglycemic activity of 70% ethanolic extract of Dregea volubilus Benth. leaves in alloxan induced diabetic rats. Phytochemical constituents of the leaves were investigated by using the methods of Harborne (1984) and Physicochemical standards of Unani Formulations (1987). Acute toxicity study of the extract of the leaves in mice was done according to Organization for Economic Co-operation and Development guideline (OECD 423). Hypoglycemic activity was determined in alloxan induced diabetic rats. Hyperglycemia was induced in adult healthy albino rats of both sexes by single intraperitoneal injection of 5% alloxan monohydrate (120 mg/kg).