Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2023

Myanmar   Health   Sciences   Research   Journal

Volume   35,  Number   1-3

TITLE:   Community-based Cervical Cancer Screening Using Cobas Human Papillomavirus (HPV) Test and Liquid Based Cytology (LBC) in Married Women Living in North Okkalapa Township, Yangon
AUTHOR:   Mu Mu Shwe1*, Kyi Kyi Nyunt2, Lin Pa Pa Aye1, Kham Mo Aung1, Myat Noe Swe2, Ni Ni Aung2, Ohnmar Sein3, Win Maw Tun1 and Kyaw Zin Thant1
SOURCE:   Myanmar Health Sciences Research Journal, 2023; 35(1-3):10-18
ABSTRACT:  

Cervical cancer is caused by persistent infection with high-risk human papillomavirus (hrHPV) types. This study aimed to perform the community-based cervical cancer screening using Cobas HPV test and liquid-based-cytology (LBC) in married women by a cross-sectional descriptive method. A total of 312 married women were screened using LBC in 2017. Among them, 220 women aged between 30-49 years were also investigated using Cobas HPV test. Cervical cells were obtained from the cervix by sterile disposable cytobrush and collected in Cobas PCR-cell-collection-media. HPV DNA testing was performed by Cobas HPV Test. It is an automated, polymerase-chain-reaction and nucleic-acid-hybridization test for the detection of 14 hrHPV types in a single analysis. It identifies HPV-16 and HPV-18 specifically which are associated for over 70% of cervical cancer while concurrently detecting other 12 hrHPV types (-31,-33,-35,-39,-45,-51,-52, -56,-58,-59,-66-and-68) as pooled-12-hrHPV. In this study, hrHPV was identified in 5.5% (12/220) of women in general population of Kyauk Ye Twin Ward. Among HPV positive cases, pooled-12-hrHPV types were 66.7%, HPV-16 (25%) and HPV-18 (8.3%). Using LBC (Bethesda-system), negative-for-intraepithelial-lesion-or-malignancy (NILM) was 79.5% (248/312). Epi-thelial cell abnormalities such as atypical-squamous-cells and/or atypical-glandular-cells (ASC/AGC), low-grade-squamous-intraepithelial-lesion (LSIL) and high-grade-squamous-intraepithelial-lesion (HSIL) were detected 11.9% (37/312), 7.4% (23/312) and 1.3% (4/312), respectively.