Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

Next Prev

Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2020

Myanmar   Health   Sciences   Research   Journal

Volume   32,  Number   2

TITLE:   Hypolipidemic Activity of Combination of Extract of Zingiber officinale Rosc. (Ginger) Rhizomes and Citrus aurantifolia Linn. (Lime) Fruits Juice on Triton-Induced Hyperlipidemic Rats
AUTHOR:   Khine Khine Lwin, Mu Mu Sein Myint, Khin Phyu Phyu1, Aye Win Oo1, Phyu Phyu Win1, Khin Tar Yar Myint1, Myint Myint Khine, Hlaing Myat Thu, Kyaw Zin Thant
SOURCE:   Myanmar Health Sciences Research Journal, 2020; 32(2): 173-179
ABSTRACT:  

This study was done in 2016-2017to investigate the hypolipidemic activity of combination of watery extract of ZingiberofficinaleRosc.(ginger) rhizomes and fruit juice of Citrus aurantifolia Linn. (lime) in triton-induced hyperlipidemic rats. Acute oral toxicity test of combination of watery extract of ginger and lime juice was done on albino mice by the method of Litchfield and Wilcoxan (1949). Phytochemical tests of the combination of ginger extract and lime juice were also performed. Twenty-four Wistar albino rats of both sexes were randomly divided into four groups consisting six rats each. Group 1 was normal control group. Group 2 served as triton-induced hyperlipidemic control group. Group 3 was given combination of watery extract of ginger and lime juice (10g/kg) and Group 4 was given standard drug (atorvastatin 30mg/kg). Fasting serum lipid levels (total cholesterol, high density lipoprotein (HDL) and triglyceride) of all rats were determined with Semi Auto Chemistry Analyzer. Low density lipoprotein (LDL) levels of the rats were calculated by using formula. It was observed that LD50 value of the combination of ginger and lime was more than
16 g/kg. The results showed that after two weeks of pretreatment, serum total cholesterol and LDL levels were reduced significantly in the combination of ginger extract and lime juice (10 g/kg) treated group (p<0.001) when compared with hyperlipidemic control group by using unpaired Student`s t test. In conclusion, the combination of watery extract of ginger and lime juice possessed significant hypolipidemic effect on serum total cholesterol and LDL levels in triton-induced hyperlipidemic rats.