Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

Next Prev

Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2020

Myanmar   Health   Sciences   Research   Journal

Volume   32,  Number   2

TITLE:   Determination of Hair Staining Effect and Lawsone Content from Leaf Extracts of Lawsonia inermis Linn.
AUTHOR:   Thiri Hlaing, Khin Tar Yar Myint, San San Wai, Khine Sabel Aung, Aye Aye Phyu Mar Mar Myint, Aye Win Oo, Kyi Kyi Oo, Soe Myint Aye
SOURCE:   Myanmar Health Sciences Research Journal, 2020; 32(2):159-165
ABSTRACT:  

Cosmetic beautification outcomes are associated with medicinal effects. Continuous usage of synthetic dye on natural hair causes many side effects such as skin irritation and erythema. The side effects of the synthetic dye limit its use by health conscious customers throughout the world. Concern for the environment has also created an increasing demand for natural dyes, which are friendlier to the environment than synthetic dyes. Thus, the aim of this study was to determine hair staining effect and Lawsone content from leaf extracts of Lawsonia inermis L. This study was done from January 2017 to December 2017.The dried leaf powder and different extracts were screened for phytochemical constituents. Hair staining effect of the three different extracts was evaluated by in-vitro test with human hair samples. Among them, hair staining effect of defatted 50% ethanolic extract was observed to be semi-permanent and good staining effect (4/5 to 4 experimental grade scales). In rabbit skin irritation study, defatted 50% ethanolic extract had negligible skin irritancy (PII<0.4). Isolated Lawsone compound was identified by UV-Vis spectrophotometry and FT-IR spectrometry.Quantitative determination of lawsone compound in three different extracts was done by TLC scanner 4 (CAMAGE). Lawsone contents in defatted 97% ethanolic extract, defatted methanolic extract and defatted 50% ethanolic extract were 2.2 μg/g, 1.4 μg/g and 0.8 μg/g, respectively. Therefore, the leaf extract of Lawsonia inermis L. can safely be used as an alternative to synthetic hair dye chemical of hair color cosmetics because it gives the beautiful and long-lasting hair color without any skin irritation.