Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2020

Myanmar   Health   Sciences   Research   Journal

Volume   32,  Number   2

TITLE:   Molecular Diagnosis of Haemoglobin E Among Pregnant Women Attending 300-Bedded Pyin Oo Lwin General Hospital
AUTHOR:   Khin Moe Aung, Nandar Ko,Thei Thei Moe Han, Myint Myint Khaing, Htay Htay Kywe, Myitzu Tin Oung, Htwe Htwe, & Khin Saw Aye
SOURCE:   Myanmar Health Sciences Research Journal, 2020; 32(2):105-111
ABSTRACT:  

Haemoglobin E (HbE) is the most common Hb variant found among Southeast Asian populations. Myanmar also has high prevalence of important haemoglobinopathies: HbE - 1 to 28.3% accounting for 1 to 4.9 births per 1000 infants with a major haemoglobinopathy. This study was conducted to determine the prevalence of HbE among pregnant women attending 300-bedded PyinOoLwin General Hospital. This hospital-based cross-sectional descriptive study was done in 2019.
A total400 apparently healthy pregnant women (17 to 44 years) with the mean age 27.51 years (SE - 6.14 years) were involved. Four milliliters of venous blood were collected andhaematological parameters were determined by automated haematology analyzer (Pentra-60) and blood film examinations were done. Then, hypochromic microcytic anaemia were assessed for serum ferritin by fully automated immunology analyzer (Mini Vidas) and molecular diagnosis of HbE was identified by using ARMS-PCR reaction. Data entry and analysis was done by SPSS software 20.0 version. The overall prevalence of anaemia was 39.0% (156/400) in which iron deficiency anaemia (IDA) was occurred in 70 women (17.5%) and the rest (86, 21.5%) were not iron deficient anaemia, respectively. The overall percentage of HbE in this study was found to be 27.6% (43/156) among the HMA pregnant women. The ratio of IDA: non-IDA cases among the pregnant women were 1: 1.2. Therefore, this study highlighted that one of the main causes of anaemia was haemoglobinopathy and remains a common health problem among pregnant women. For prevention of thalassaemia major in maternal child health care units in our country, prenatal screening and family counseling of beta and alpha thalassaemia carriers inpregnant women is highly recommended.