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Archives 2020
Myanmar Health Sciences Research Journal
Volume 32, Number 1
TITLE: Antibacterial Activity of Coriandrum sativum L. Extracts (Nannan)
AUTHOR: Khin May Thi, Soe Myint Aye, Aye Thida Htun, Chaw Su1, Ei Ei Htway, May Thandar Htun, Zin Nwe Soe & Khin Saw Aye
SOURCE: Myanmar Health Sciences Research Journal, 2020; 32(1):73-77
ABSTRACT:
Coriandrum sativum L. is consumed in human diet, is a good source of minerals and vitamins and widely distributed in Myanmar. In this study, antibacterial activities of different extracts (70% ethanol and 70% methanol) of Coriandrum sativum L. (whole plant) were studied on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Ceftriaxone was used as positive control. The antibacterial activity of Coriandrum sativum L. extracts was determined by agar disc diffusion method. The 70% ethanolic extract showed zone of inhibition 8 mm and 70% methanolic extract showed 9 mm on E. coli, S. aureus and P. aeruginosa. Broth dilution method was used for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Coriandrum sativum L. MIC and MBC of ethanolic extract and methanolic extracts of Coriandrum sativum L. were 400 mg/ml on E. coli, S. aureus and P. aeruginosa. Phytochemical analysis of Coriandrum sativum L. was also carried out and alkaloids, glycosides, steroids, cardiac glycosides, amino acids, starch, phenols, tannin and carbohydrates were detected, and flavonoids, saponin, protein, resins and cyanogenic glycosides were not detected. Antibacterial activity of Coriandrum sativum L. may be due to the presence of phenols. Therefore, this study provided useful information about antibacterial activity of different extracts of Coriandrum sativum L. (whole plant)
SUBJECT HEADINGS: Antibacterial activity, Coriandrum sativum L., Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli
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