Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2020

Myanmar   Health   Sciences   Research   Journal

Volume   32,  Number   1

TITLE:   Antibacterial Activity of Coriandrum sativum L. Extracts (Nannan)
AUTHOR:   Khin May Thi, Soe Myint Aye, Aye Thida Htun, Chaw Su1, Ei Ei Htway, May Thandar Htun, Zin Nwe Soe & Khin Saw Aye
SOURCE:   Myanmar Health Sciences Research Journal, 2020; 32(1):73-77
ABSTRACT:  

Coriandrum sativum L. is consumed in human diet, is a good source  of minerals and vitamins and widely distributed in Myanmar. In this study, antibacterial activities of different extracts (70% ethanol and 70% methanol) of Coriandrum sativum L. (whole plant) were studied on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Ceftriaxone was used as positive control. The antibacterial activity of Coriandrum sativum L. extracts was determined by agar disc diffusion method. The 70% ethanolic extract showed zone of inhibition 8 mm and 70% methanolic extract showed 9 mm on E. coli, S. aureus and P. aeruginosa. Broth dilution method was used for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Coriandrum sativum L. MIC and MBC of ethanolic extract and methanolic extracts of Coriandrum sativum L. were 400 mg/ml on E. coli, S. aureus and P. aeruginosa. Phytochemical analysis of Coriandrum sativum L. was also carried out and alkaloids, glycosides, steroids, cardiac glycosides, amino acids, starch, phenols, tannin and carbohydrates were detected, and flavonoids, saponin, protein, resins and cyanogenic glycosides were not detected. Antibacterial activity of Coriandrum sativum L. may be due to the presence of phenols. Therefore, this study provided useful information about antibacterial activity of different extracts of Coriandrum sativum L. (whole plant)


SUBJECT HEADINGS:   Antibacterial activity, Coriandrum sativum L., Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli
FULL TEXT:  

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Subject Headings : Antibacterial activity, Coriandrum sativum L., Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli Full Text : 12Khin May Thi.pdf -->

Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar