Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2020

Myanmar   Health   Sciences   Research   Journal

Volume   32,  Number   1

TITLE:   Serum High Density Lipoprotein Subfractions and Other Lipid Parameters in Coronary Artery Diseases
AUTHOR:   Hein Ko Oo, Sint Sint Tun, Theingi Myint & Kyu Kyu Maung
SOURCE:   Myanmar Health Sciences Research Journal, 2020; 32(1):58-65
ABSTRACT:  

Conventionally, high density lipoprotein cholesterol (HDL-C) level was measured in prediction of coronary artery disease (CAD). Because HDL particles are continuously remodeled in terms of lipid and apolipoprotein composition, the distribution of cholesterol in HDL subclasses; HDL2- Cholesterol (HDL2-C) and HDL3-Cholesterol (HDL3-C) levels are more predictive values for occurrence of CAD than total HDL-C level. The aim of this study was to investigate the HDL2-C and HDL3-C levels in patients who had undergone coronary angiogram in Yangon General Hospital and to investigate the association between serum HDL2-C level, HDL3-C level and occurrence of CAD. Pre-procedural fasting serum were collected from 132 patients and analyzed for HDL2-C, HDL3-C, total cholesterol (TC), total HDL cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and triglyceride (TG). The TC, HDL-C and TG levels were determined by enzymatic colorimetric method and LDL-C levels were calculated from the above-mentioned lipid parameters. The median serum HDL-C levels were significantly lower in CAD patients (35.73 mg/dl) than patients with normal angiogram (40.95 mg/dl). The median serum HDL2-C levels were 11.93 mg/dl in significant CAD patients and 18.39 mg/dl in patients with normal angiogram. The median serum HDL3-C levels were 22.54 mg/dl in significant CAD patients and 22.93 mg/dl in patients with normal angiogram. Patients with significant CAD had significantly lower median serum HDL2-C level than patients with normal angiogram (p<0.01). There was no significant difference in median HDL3-C level between patients with significant CAD and patients with normal angiogram (p>0.05). There was significant association between CAD and decreased level of HDL2-C (p<0.05). The fall in serum HDL 2-C level is more likely to be predictive of CAD risk than HDL3-C level. Therefore, low serum HDL2-C level is associated with increased CAD risk.