Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

Next Prev

Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2018

Myanmar   Health   Sciences   Research   Journal

Volume   30,  Number   3

TITLE:   Subclinical Thyroid Dysfunction and Cognitive Function in Myanmar Elderly
AUTHOR:   Khin Mi Mi Lay, Thura Tun Oo, Win Lai Lai Sint, Sandar Win, Htike Htike Soe, Khin San Lwin, Htet Htet Lwin, Theingi Thwin & Kyaw Zin Thant
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 30, No. 3, 2018
ABSTRACT:   Although both subclinical hyper- and hypo-thyroidism have been implicated as risk factors for cognitive decline, the clinical relevance of this finding is still controversial. This cross-sectional analytical study aimed to find out the association between subclinical thyroid dysfunction and cognitive function of elderly people. A total of 157 elderly (60-70 years old, 47 men and 110 women) from Thabawa Meditation Center, Thanlyin participated in the study. Serum triiodthyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) were measured as indicators for thyroid function and determined by direct sandwich ELISA method. Cognitive function was assessed by using mini-mental state examination (MMSE). It was found that 85.99% of the elderly had normal thyroid function and 14.01% had thyroid dysfunction. The most common was subclinical hypothyroidism (11.46%), followed by subclinical hyperthyroidism (1.27%) and overt hyperthyroidism (1.27%), respectively. Among the elderly, 49.04% had normal cognitive function (MMSE score ≥28), 38.85% had impaired cognitive ability (MMSE score between 27-24) and 12.11% had dementia (MMSE score ≤23). Although no significant correlation was found between T3, T4, TSH level and MMSE score in the whole study group, a moderate degree of significant negative correlation between TSH level and MMSE score (r=-0.49, p<0.05, n=18) was found in those with subclinical ypothyroidism. This could be simply due to the fact that TSH is the most sensitive measure of thyroid status. This study pointed out that subclinical hypothyroidism is the most prevalent thyroid dysfunction among the asymptomatic elderly and those with subclinical hypothyroidism were not more likely to have cognitive impairment.
SUBJECT HEADINGS:   Elderly, Subclinical thyroid dysfunction, Cognitive function
FULL TEXT: