Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2017

Myanmar   Health   Sciences   Research   Journal

Volume   29,  Number   1

TITLE:   Identification of Dengue Serotypes in Children with Dengue Infection at Yangon Children’s Hospital in 2015
AUTHOR:   Win Kay Khine, Theingi Win Myat, Hlaing Myat Thu, Wah Win Htike, Khine Mar Oo, Khin Mar Aye, Mo Mo Win, Ye Myint Kyaw & Kyaw Zin Thant
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 29, No. 1, 2017
ABSTRACT:   Dengue is the most important arthropod-borne viral infection of humans. All four dengue virus serotypes (DENV1-DENV4) were circulating in Myanmar and DENV-1 was the most frequently isolated one starting in 2001. To identify dengue serotype, a total of 234 paired serum samples were collected from patients with clinically suspected dengue infection attending Medical Wards of Yangon Children’s Hospital from January to July 2015. The convalescent serum samples (S2) were tested by Immuno-chromatographic tests. The proportion of serologically confirmed cases was 76% (178 out of 234). Out of these, 178 seropositive cases, 46(26%) were diagnosed as primary and 132(74%) as secondary dengue infection. Among 46 cases of primary infection, 24(52%) were DHF grade I, 10(22%) were grade II, grade III and grade IV were 7(15%) and 5(11%), respectively. Among 132 cases of secondary infection, 72(55%) were DHF grade I, 24(18%) were grade II, 19(14%) were grade III and 17(13%) were grade IV. DHF GI and DHF GII (mild form of dengue) were the most common in both infections. The corresponding acute phase serum (S1) of the ICT positive (S2) samples with <5 fever days were selected for virus isolation by tissue culture in C6/36 mosquito cell lines and further typed with serotype specific monoclonal antibodies to four dengue viruses by using Indirect Immunofluorescence Assay. Out of 103, dengue virus was isolated from 20 samples accounting for 19% isolation rate. Among isolated dengue viruses, 14(70%) were DENV-1, 2(10%) were DENV-2, 1(5%) was DENV-3 and 3(15%) were found to be of concurrent infections (1 case of DENV-1+DENV-2 and 2 cases of DENV-1+DENV-4). In Myanmar, since 2001 except in 2007, the predominant one was serotype 1. The present study showed that it has not changed. Concurrent infections were also detected in 2015 but they did not associate with severe form of disease.
SUBJECT HEADINGS:   Serotype, Primary infection, Secondary infection, Dengue
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