Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2017

Myanmar   Health   Sciences   Research   Journal

Volume   29,  Number   1

TITLE:   Serum Trace Elements between Pre-eclamptic Women and Apparently Healthy Pregnant Women
AUTHOR:   Khin Moe Aung, Aung Kyaw Kyaw, Myitzu Tin Oung, Than Lwin, Yu Yu Aung, Zin Mon Kay Khine Win, Tin Tin Thein & Khin Htar Yi
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 29, No. 1, 2017
ABSTRACT:   Pre-eclampsia is a leading cause of maternal mortality and morbidity. This hospital- and laboratory-based comparative study was conducted at Department of Medical Research (Pyin Oo Lwin Branch) and Central Women’s Hospital (Mandalay) from September 2010 to February 2011. The purpose of this study was to find out the role of serum trace elements in the diagnosis of pre-eclampsia. Fifty pre-eclamptic pregnant women of any gestational period admitted to the Obstetric Wards of Central Women’s Hospital (Mandalay) were enrolled as participants (50 cases) and fifty apparently healthy pregnant women attending the antenatal clinics with those same age, parity and gestational period were also enrolled as control group (50 cases) and systematic sampling procedure was used in this study. Diagnosis and severity of disease was classified according to American College of Obstetrician and Gynaecologist (ACOG) guideline. The serum trace elements levels were determined by Atomic Absorption Spectro-photometer. Serum magnesium and zinc levels in normal, mild and severe patients were 34.38±8.28 mg/l, 35.40±11.55 mg/l, 35.79±11.34 mg/l and 0.57±0.14 mg/l, 0.63±0.14 mg/l, 0.63±0.17 mg/l, respectively. There was no significant difference in mean serum magnesium and zinc levels between normal women and women with mild and severe pre-eclampsia (p>0.05). Areas under the receiver operating characteristics curve (ROC curve) for serum magnesium and zinc were 0.43 and 0.37 and these markers did not reach the acceptable limit for applying as the diagnostic test.
SUBJECT HEADINGS:   Pre-eclampsia, Pregnant women, Magnesium, Zinc
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar