Myanmar Health Sciences Research Journal
Next Prev
Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2015

Myanmar   Health   Sciences   Research   Journal

Volume   27,  Number   3

TITLE:   Antioxidant Activity of Betel Leaf (Piper betle Linn.)
AUTHOR:   May Thandar Htun, Wai Mi Aung, Aye Aye Phyu, Aye Thida Htun, Swe Zin Aung, Zin Nwe Soe, Swe Swe & Yi Yi Myint
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 27, No. 3, 2015
ABSTRACT:   Piper betle Linn. belongs to the family Piperaceae is an evergreen and perennial creeper with glossy heart-shaped leaves and white catkin. The leaves of Piper betle Linn. have been traditionally known for its various therapeutic uses such as stimulant, antitussive, carminative, expectorant, antihyperglycemic, antibacterial and antifungal. In the present study, the leaves of Piper betle Linn. were collected from cultivated sources in Kyaukse Township, Mandalay Region. Botanical identification of plant was done by morphological examinations. Phytochemical characters were studied by using reference analytical methods. The different extracts were obtained by percolation and reflux method. Antioxidant activities of fresh juice, ethanol extract and aqueous extract of Piper betle Linn. was determined by using 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) assay and ascorbic acid was used as specific standard. While IC50 of ascorbic acid was 1.66 µg/ml, the concentration of Piper betle Linn. needed for 50% inhibition (IC50) was found to be 92 µg/ml, 94 µl/ml, 95 µg/ml for ethanol extract, fresh juice and aqueous extract, respectively. The antioxidant activity of ethanol extract of Piper betle Linn. was found to be slightly more than fresh juice and aqueous extract. From above data, fresh juice of Piper betle Linn. possesses antioxidant activity which demonstrates the possibility of the use of this plant as supplementary medicine.
SUBJECT HEADINGS:   Antioxidant activity, Piper betle Linn., DPPH assay, IC50
FULL TEXT:  

Back to Articles

Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar