Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2015

Myanmar   Health   Sciences   Research   Journal

Volume   27,  Number   3

TITLE:   Antimicrobial Activity of Betel Leaf Extracts
AUTHOR:   Aye Thida Htun, Saw Myat Thwe, Phyo Mon Oo, Wai Mi Aung, May Thndar Htun, Moh Moh Lwin, Rai Kit, Swe Swe & Yi Yi Myint
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 27, No. 3, 2015
ABSTRACT:   Piper betle L. is a well-known medicinal plant and widely distributed in Myanmar. In this study, antimicrobial activity of different extracts (95% ethanol and distilled water) and fresh juice of Piper betle L. leaf was studied on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Ceftriaxone was used as positive control. Antimicrobial activity of Piper betle L. leaf extracts was determined by agar disc diffusion method. Among the different extracts and fresh juice, 95% ethanolic extract showed more larger zone of inhibition, i.e., 7 mm to 12 mm for Staphylococcus aureus and Pseudomonas aeruginosa and 8 mm to 13 mm for Escherichia coli. Fresh juice (up to 30 μl) did not show the significant zone of inhibition on above microorganisms. Broth dilution method was used for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ethanolic and aqueous extract of betel leaf. Although MIC and MBC of aqueous extracts did not show the concentration up to 11 mg/ml, MIC of ethanolic extract was observed in the range from 1 mg/ml to 8 mg/ml and MBC from 2 mg/ml to 9 mg/ml. Phytochemical analysis of Piper betle L. leaf was carried out according to the quality control method of World Health Organization. The presence of phenolic and tannin compounds seemed to exert antimicrobial activity. So, this study will provide referential information about the antimicrobial activity of different extracts and fresh juice of Piper betle L.
SUBJECT HEADINGS:   Piper betle L., Antimicrobial activity, Phenol, Tannin
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