Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   1989

Myanmar   Health   Sciences   Research   Journal

Volume   1,  Number   3

TITLE:   Acetaminophen (paracetamol) pharmacokinetics in contraceptive pill-using Myanmar women.
AUTHOR:   Cho Cho Myint; Aung Naing; Tha, Saw Johnson; Khin Kyi Kyi
SOURCE:   Myanmar Health Sciences Research Journal. 1989; 1(3): 153-156
ABSTRACT:   Acetaminophen (paracetamol) pharmacokinetic study was made on a total of 16 healthy adult Myanmar women of reproductive age, half of whom were pretreated chronically for 6 month with an oral contraceptive steroid (OCS), namely, Combination 5. Single oral dose (930 mg) of acetaminophen showed similar extent of maximum plasma acetaminophen concentration in either group. However, the OCS causes significant effect (p0.05) on plasma acetaminophen resulting in shortening of half-life by 21.6% and augmentation of clearance by 5.9%. The OCS affected predominantly the sulphate conjugation of acetaminophen. In regimen requiring repeated dosing, acetaminophen should be administered more frequently in the pill-users.
SUBJECT HEADINGS:   Acetaminophen. Pharmacokinetics. Contraceptives, Oral.
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