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Archives 1989
Myanmar Health Sciences Research Journal
Volume 1, Number 3
TITLE: Clinical significance of IFAT test on falciparum malaria patients
AUTHOR: Tin Shwe; Pe Than Myint; Myint Lwin; Ye Htut
SOURCE: Myanmar Health Sciences Research Journal. 1989; 1(3): 117
ABSTRACT: The indirect fluorescent antibody technique (IFAT) has been successfully used in sero-epidemiological studies of malaria (1, 2). Whether its clinical application to help in diagnosis or as indicator of prognosis was studied on a total of 83 patients (belonging to different categories of clinical severity) and 100 controls (contact of malaria patients) were studied. There was no relationships between severity of the categories and the IFAT¬positivity rate. Geometric Mean Reciprocal Titre (GMRT) of the patients at day 0 of hospital admission varied widely in different groups of patients (Table 1). A time-course profile study on 9 patients from category (3) and 26 patients from category (2) were follow¬ed on day 0, 3, 7, 14, 21 and 28. There were no significant alternations in the level of GMRT during the study period. The study concluded that IFAT test is of no help in diagnosis and GMRT cannot assist the prognosis of P. falciparum malaria patients.
SUBJECT HEADINGS: Malaria, Falciparum. Fluorescent Antibody Technique.
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