- To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
- To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
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Archives 1990
Myanmar Health Sciences Research Journal
Volume 2, Number 3
TITLE: Vero cell cytotoxic Escherichia Coli isolated from children with diarrhoea.
AUTHOR: Mar Mar Nyein; Kyu Kyu Mar; Tin Aye; Hayashi, H
SOURCE: Myanmar Health Sciences Research Journal. 1990; 2(3): 118-129
ABSTRACT: A total of 616 isolates of Escherichia Coli from 90 diarrhoea cases and 87 control cases were included in this study. Vero cells were cultured in microtitre plates. E. coli toxin was produced by growing in Trypticase Soy Broth with vigourous shaking. It was demonstrated that 17 out of 55 cases (30.9%) from diarrhoea group and 7 out of 70 cases from control group (10%) were verotoxic and these were not Enteropathogenic (EPEC) not Enterotoxigenic (ETEC) group of E. coli. It was also observed that in diarrhoea group of study, 5 out of 9 cases of (EPEC) and 2 out of 8 cases of (ETEC) and 8 out of 18 cases of both (EPEC + ETEC) were verotoxic. Other bacteria tested failed to produce toxic substances which could produce cytopathic effect on Vero cells.
SUBJECT HEADINGS: Vero Cells. Cytotoxins. Escherichia Coli. Diarrhea. Child.
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