Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   1991

Myanmar   Health   Sciences   Research   Journal

Volume   3,  Number   3

TITLE:   Pharmacognostical and pharmacological study on Taw-Kyet-Thun reputed for anthelminthic action.
AUTHOR:   Aye Than; Thida Swe; Chit Maung; Mya Bwin
SOURCE:   Myanmar Health Sciences Research Journal. 1991; 3(3): 124-128
ABSTRACT:   Taw-Kyet-Thun, an indigenious Myanmar medicine plant whose bulb is being claimed by the country-folks to be effective in purging intestinal roundworms, was identified to be Urginea indica Kunth. Phytochemically, it consists of steroidal and flavonoid glycosides. On the in vitro test model of Asxaris suum the 50% alcoholic bulb extract indicated its anthelminthic efficacy by significantly immobilizing the parasite within 4-6 hours, with respect to both the frequency and the magnitude of motility of the worm; however, an initial stimulatory action on the parasite was observed, a situation which is undesirable. Acute toxicity of the bulb extract tested on mice showed the LD 50s to be 52(41-66) mg/kg when administered intraperitoneally, and 680 (555-833) mg/kg, orally.
SUBJECT HEADINGS:   Plants, Medicinal. Anthelmintics. Herbs, Medicinal. Pharmacognosy. Intestinal Diseases, Parasitic.
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar