Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   1992

Myanmar   Health   Sciences   Research   Journal

Volume   4,  Number   1

TITLE:   Effect of dietary iron defiency on some enzyme levels in growing rats.
AUTHOR:   Tin Win; Aye Kyaw; Hla Pe
SOURCE:   Myanmar Health Sciences Research Journal. 1992; 4(1): 52-60
ABSTRACT:   Primary derangement in the levels of iron enzymes in iron deficiency have been reported by various workers. The present study was undertaken to deternime whether secondary derangements in the levels of other non-iron enzymes could accompany in the primary derangement. Three groups of rats were fed synthetic diet for 85 days. Group I received the iron deficient diet ad libitum, group II was pair fed with group I but received supplemented iron and group III received the iron supplemented diet ad libitum. The following were the mean values of some biological data at time of sacrifice. Body weight of group I, II and III were 82.5 g, 96.5g, 108.5g and haemoglobin , 7.2 g. , 14,1 g. and 14.8 g. respectively. Enzyme levels were measured in different tissues of the three groups of rats. The levels of hepatic iron enzyme, catalase, as well as non-iron enzymes, glucose 6 phosphate dehydrogenase (G6PD), glutamate dehydrogenase (GD) and malate dehydrogenase (MD) were significantly decreased in the iron deficient group. The decrease was more pronounced in the levels of catalase. However, lactate dehydrogenase did not show any significant changes. The enzymes were unaffected in kidneys and spleen except catalase, which decreased in group I.
SUBJECT HEADINGS:   Iron, Dietary. Iron-deficiency. Protein Deficiency. Immunoenzyme Techniques.
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar