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This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

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Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

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Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2003

Myanmar   Health   Sciences   Research   Journal

Volume   15,  Number   1-3

TITLE:   A study of the anti-inflammatory effect of Zingiber officinale Roscse (Gyin-sein) on albino rats.
AUTHOR:   Khine Khine Lwin; Mya Mya Than; Khin Chit; Mu Mu Sein Myint; Aye Than; Aye Aye Thein
SOURCE:   Myanmar Health Sciences Research Journal. 2003; 15(1-3): 25-30
ABSTRACT:   This study was aimed to investigate the anti-inflammatory activity of Zingiber officinale Roscoe (Ginger) on caiTageenan-induced paw inflammation in albino rats. Both aqueous extract and ethanolic extract of the dried rhizomes of Ginger were used. Plethysmographic apparatus was used to measure the volume changes of earrageenan-induced rat's paws oedema. Anti-inflammatory actions of both extracts were investigated by using 3 dose levels i.e. 3g/kg, 1.5 gikg, 0.75g/kg body weight, orally and compared with that of aspirin 300mg/kg. Significant anti-inflammatory actions were found with both extracts of Ginger. It was found that the anti- inflammatory actions of both extracts were found to have dose-response relationship in nature. The results also indicated that anti-inflammatory action of ethanolic extract of Ginger was found to be superior to that of aqueous extract. But anti-inflammatory effects of both extracts of Ginger were inferior to that of standard reference drug, aspirin. The actions of ethanolic extract and aqueous extract were (0.49-0.66) times and (0.52-0.55) times that of aspirin respectively. Acute toxicity studies and general pharmacological screening tests of both extracts on albino mice showed no lethality and no abnormal changes. The actions of both extracts of Ginger may he due to one or more compounds obtained in these extracts i.e. saponins, alkaloids, resins, steroids and flavonoids according to the phytochemistry. Therefore, it can be concluded that both extracts of Ginger may be beneficial for use in joint pain and inflammation.
SUBJECT HEADINGS:   Plants, Medicinal. Anti-Inflammatory Agents.
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