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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2004

Myanmar   Health   Sciences   Research   Journal

Volume   16,  Number   1-3

TITLE:   Bacteriological study of sputum smears positive follow-up pulmonary tuberculosis patients attending Tuberculosis Centre, Yangon Division.
AUTHOR:   Wah Wah Aung
SOURCE:   Myanmar Health Sciences Research Journal. 2004; 16(1-3): 23-29
ABSTRACT:   This study was carried out in Tuberculosis Centre, Yangon Division from December 2001 to January 2003. Sputum smear microscopy and drug susceptibility pattern to seventy follow-up pulmonary tuberculosis patients (46 Category 1 patientsa and 24 Category II patients) still sputum smear positive after initialintensive phase of anti-tuberculosis treatment were studied to determine the possible bacteriological factors related to slow rate of sputum conversion and to detect drug resistant cases among them. The results showed that heavy initial baciillary load was the most common cause for slow rate of sputum conversion after initial phase. Multi-drug resistant tuberculosis cases were detected in 4.6% (2 cases) of Category I follow-up patients and 12.5% (3 cases) of Category II follow-up patients. Resistance to one drug were seen in 22.7% (10 cases) of Category 1 patients and 29.1% (7 cases) of Category II patients. Based on the results of our study it is suggested that performing of drug susceptibility testing on follow-up pulmonary tuberculosis patient’s still sputum smear positive at the end of initial intensive phase treatment could detect drug resistance in the early stage and could be ultimately one of the means of reducing MDR-TB country wide.
SUBJECT HEADINGS:   Tuberculosis. Sputum. Tuberculosis, Pulmonary.
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