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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2005

Myanmar   Health   Sciences   Research   Journal

Volume   17,  Number   3

TITLE:   The effect of maternal malnutrition on physical growth of Wistar rats.
AUTHOR:   Tin Tin Yi; Ye Tint Lwin; Khin Mar Cho; Mi Mi Nwe; Ni Ni Than; Lwin Lwin Maw; Wah Wah Win; Soe Min Thein
SOURCE:   Myanmar Health Sciences Research Journal. 2005; 17(3): 149-153
ABSTRACT:   The study was conducted to find out the effect of maternal malnutrition during the first and third trimesters of pregnancy on body weight and length of the offsprings up to adult life. Thirty Wistar strain female rats were randomly divided into 3 groups and were allowed to become pregnant. Forty percent restriction of food intake was done during the first trimester in test I group and during the third trimester in test II group while one group, the control group, was given food ad libitum throughout pregnancy. The offsprings of all three groups were allowed to take food ad libitum. Mean birth weight, mean weaning weight, mean weaning length and mean adult length of test II group were significantly lower (p<0.0001) than those of the control group (4.56g vs 5.46g, 19.57 g vs 23.84 g, 14.45 mm vs 16.08 mm and 39.78 mm vs 41.15 mm respectively). However, mean birth weight (5.4g), mean weaning weight (24.78 g), mean weaning length (16.08 mm) and mean adult length (40.82 mm) of test I group were more or less similar to those of control group but mean adult weight of test I group (263.04g) was significantly greater (p<0.004) than that of the control group (237.65g).From this study, it was found that maternal malnutrition during third trimester can cause defective physical growth of off-spring.
SUBJECT HEADINGS:   Nutrition Disorders. Infant, Low Birth Weight. Growth.
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