Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2006

Myanmar   Health   Sciences   Research   Journal

Volume   18,  Number   3

TITLE:   Comparing the efficacy of initial single dose rectal artesunate versus single dose intravenous artesunate at 24 hours and after full consolidation treatment in both groups with intravenous artesunate in severe falciparum maliaria in adults.
AUTHOR:   Win Win Myint; Khin Phyu Pyar; Myat Phone Kyaw; Than Htut; Khin Nyo; Malar Than
SOURCE:   Myanmar Health Sciences Research Journal. 2006; 18(3): 155-160
ABSTRACT:   The mortality rate of severe falciparum malaria, once vital organ dysfunction occurs, is as high as 30%. In remote areas, transport problems lead to high morbidity and mortality. Rectal artesunate, single dose is recommended for initial management of severe falciparum malaria especially in remote areas, to be followed by consolidation treatment at the nearest health care facility. A randomized controlled trial of rectal artesunate and parenteral artesunate was studied on 60 severe falciparum malaria cases admitted to DSGH. Test drug was Plasmotrim 50 mg rectocap 200 mg stat dose. Control drug wasinjectionArtesunate120 mgintra venous infusion, both arms followed at 24 hours by injection Arte-sunate 60 mgintravenousinfusion,repeated 12 hourly(total=480 mg ), plus tetracycline orclindamycin250 mg 6 hourly for 7 days. Parasite clearance time in rectal artesunate was 46.3 hours and IV artesunate group was 49.1 hours and the 24 hours parasite clearances were 81.7% and 76.3% respectively (p>0.5). There was no difference in the 48 hour parasite clearance which were 96.2% and 96.9% respectively. Fever clearance time (FCT) was 51.5 hours with rectal artesunate compared to 30.3 hours with IV artesunate (p>0.1). The clinical success rate for rectal artesunate was similar to that of parenteral artesunate at 24 hours in this study, highlighting that it can be used effectively prior to definitive treatment to reduce malaria morbidity and mortality.
SUBJECT HEADINGS:   Malaria, Falciparum. Antimalarials.
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