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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2006

Myanmar   Health   Sciences   Research   Journal

Volume   18,  Number   3

TITLE:   Investigation of an influenza A outbreak with an unusual presentation in Kyaingtone Township during October 2005.
AUTHOR:   Kyaw Moe; Soe Lwin Nyein; Win Oo; Tin Nyunt; Soe Lwin; Hlaing Myat Thu; Win Mar Oo; Kay Thi Aye; Khin Mar Aye
SOURCE:   Myanmar Health Sciences Research Journal. 2006; 18(3): 114-121
ABSTRACT:   An investigation of an influenza outbreak, presenting with encephalopathy, in the family quarters of a military training school, Kyaingtone Township, was carried out in October 2005. Clinical, laboratory and epidemiological investigations were performed in children from the military family quarters as well as from three nearby villages. Sera samples and nasopharyngeal swabs from children, as well as sera from pigs in that area were collected. On-site rapid tests for influenza A were performed and four of nine nasopharyngeal samples were positive for influenza A. Blood samples from the children were also tested for malaria and dengue infection using near-patient tests and were negative. Timely instigation of control measures in the outbreak area averted further spread of the disease. The nasopharyngeal samples were transported to Yangon, where they were tested for avian influenza A (H5N1) employing a reverse transcriptase polymerase chain reaction and for influenza A, (H1, H3 and H5) by the indirect immuno-fluorescent assay. None of the samples were positive. Japanese encephalitis (JE) IgM enzyme immunoassay was performed on both human and pig sera and were negative. Japanese encephalitis haemagglutination inhibition (HAI) tests on pig serum samples showed two of the five pig sera to be positive. The nasopharyngeal samples were sent to the WHO National Influenza Centre for confirmation and four nasopharyngeal samples were positive for influenza A (H1N1).
SUBJECT HEADINGS:   Influenza A virus. Disease Outbreaks.
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