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Archives 2006
Myanmar Health Sciences Research Journal
Volume 18, Number 2
TITLE: Cellular immune response following Russell's viper (Daboia russelii siamensis) bites in Myanmar.
AUTHOR: Tun Pe; Aye Aye Myint
SOURCE: Myanmar Health Sciences Research Journal. 2006; 18(2): 104-108
ABSTRACT: Cellular immune response of 14 proven Russell’s viper (Daboia russelii siamensis) bite cases from Thayawady Hospital was monitored from 12 to 117 weeks following the bites in 1992 by performing mitogen induced lymphocyte proliferation to phytohaemagglutinin (PHA), pokeweed mitogen (PWM) and Russell’s viper (D.r.siamensis) venom and tolerance of PHA and PWM induced lymphocytes to venom challenge.Immune status of a Russell’s viper bite reptile keeper at 36 and 40 weeks after the bite and a venom handler of Myanmar Pharmaceutical Factory were also available for study. In general, response to PHA, PWM and venom induced lymphocyte proliferation of the victims and the venom handler was within normal range, however these parameters waned with time in the former. PHA induced lymphocytes could tolerate venom challenge more than PWM induced lymphocytes throughout the study (75-88% vs63-74%).
SUBJECT HEADINGS: Immunity, Cellular. Russell's Viper. Snake Bites.
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