Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

Next Prev

Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2006

Myanmar   Health   Sciences   Research   Journal

Volume   18,  Number   2

TITLE:   Genomic characterization of rotavirus isolates from Yangon Children's Hospital by reverse transcription polymerase chain reaction.
AUTHOR:   Kyaw Moe; Khin Mar Aye; Thandar Lwin; Win Mar Oo; Tin Tin Htwe; Thin Thin Shwe; Win Mar
SOURCE:   Myanmar Health Sciences Research Journal. 2006; 18(2): 89-94
ABSTRACT:   The intentions of the study were to establish a reverse transcription polymerase chain reaction (RT-PCR) for G and P genotyping of rotavirus isolates and to determine the distribution of human rotavirus genotypes in Yangon. This study was done on stool samples collected from under five- year-old children admitted to the Yangon Children’s Hospital for diarrhoea in 2004. After screening for rotavirus by enzyme immunoassay (EIA), 181 stool samples (32%) were randomly chosen from 564 rotavirus positive samples, for genotyping by using RT-PCR. The rotavirus positive samples were genotyped employing multiplex RT-PCR using G and P specific primers. Genotype G3 was the most common type identified (44% of samples) followed by G1 (33.3%). The genotype G1 was the predominant type in the early part of the year, but was replaced by genotype G3 from July to December 2004. The VP7 genotypes G2, G4 and G9 each represented as minor types (total < 13% of samples). Rotavirus P genotyping was attempted in 91 samples and P genotype can be ascertained in only 31 samples of which 74.2% were identified as P(8). There was no apparent pattern of P genotype distribution throughout the year. The common P and G type combinations were G1/P(8) and G3/P (8). Several unusual G and P type combinations were also identified, two of which were G1/P (4), and one sample was G3/P (4) and another belonging to G2/P (8). The distribution of G and P genotype provides important and valuable information for the development and introduction of rotavirus vaccines, the most effective strategy for the prevention of severe rotavirus diarrhoea.
SUBJECT HEADINGS:   Genomics. Rotavirus. Polymerase Chain Reaction.
FULL TEXT: