Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2006

Myanmar   Health   Sciences   Research   Journal

Volume   18,  Number   1

TITLE:   Comparison of Polymerase Chain Reaction, immunohistochemistry and conventional histopathology in the diagnosis of leprosy in Myanmar.
AUTHOR:   Khin Saw Aye; Aye Aye Win; Tin Zar Maw; Kyaw Kyaw; Khine San Ye
SOURCE:   Myanmar Health Sciences Research Journal. 2006; 18(1): 34-40
ABSTRACT:   Skin biopsy specimens were obtained from 69 leprosy patients attending at Central Special Skin Clinic, Yangon General Hospital. All biopsy samples were examined by polymerase chain reaction (PCR) using the primers amplifying the 130 base-pair fragment of the gene from the 16S ribosomal RNA of Mycobacterium leprae, hematoxylin and eosin (H&E) staining, modified Fite-Faraco (FF) technique for M. leprae and immunostaining with the antibody against the phenolic glycolipid-1 (PGL-1) and Bacille Calmette-Guerin (BCG) using ABC (Avidin Biotin Complex) method. PCR was positive for 49 (71%) of 69 specimens. In 22 (31.8%) cases, only PCR was positive for M. leprae and all other tests were negative. AFB was positive for 19 (27.5%) of 69, PGL-1 was positive for 20 (29%) of 69, BCG was positive for 27 (39%) of 69. Epithelioid cells granuloma was detected in 17 (24.6%) patients and peripheral nerve inflammatory infiltration in 42 (60%) of 69. Comparison of PCR with other method showed statistically significant difference (p<0.001). PCR has an advantage over microscopic examination in detecting M. leprae in biopsy specimens which are negative for acid-fast bacilli.
SUBJECT HEADINGS:   Polymerase Chain Reaction. Immunohistochemistry. Leprosy.
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