Original Articles 2012-02-20

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This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

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Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2006

Myanmar   Health   Sciences   Research   Journal

Volume   18,  Number   1

TITLE:   Experimental production of goat Russell's Viper antivenom.
AUTHOR:   Aye Aye Myint; Tun Pe
SOURCE:   Myanmar Health Sciences Research Journal. 2006; 18(1): 17-20
ABSTRACT:   Snakebite is an occupational hazard of farmers. Specific antidote for management of snakebite is the timely administration of an adequate dose of potent specific antivenom. Because of increased demand of antivenom requirement, ways and means to increase production of antivenom in an alternative host is sought for. Feasibility of raising Russell’s viper antivenom in goats was attempted by giving a monthly intradermal injection with a total dose of 2 mg/ml of venom adjuvant mixture at six sites per goat for two years. Antivenom level was monitored on samples collected at 8 days following each boosting by indirect enzyme immunoassay method. Results indicated that antibody reached its peak six months after immunization and sustained at its peak throughout the study. Efficacy of the salt precipitated antivenom was assessed by performing mouse protection test. ED50(s) of 5LD50 of the antivenom (6, 12 and 18 months after immunization) were 15, 15.8 and 16.2 µl respectively. This study highlights that commercial antivenom could be raised in goat, an alternative to horse and it will help in fulfilling antivenom requirement.
SUBJECT HEADINGS:   Russell's Viper. Antivenins.
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