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The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2007

Myanmar   Health   Sciences   Research   Journal

Volume   19,  Number   3

TITLE:   Detection of alpha-thalassaemia in newborn cord blood from North Okkalapa General Hospital.
AUTHOR:   Ne Win; Khine Khine Phyu; Myat Mon Oo; Mya Thandar Win; Kyaw Soe; Minn Minn Myint Thu
SOURCE:   Myanmar Health Sciences Research Journal. 2007; 19(3): 141-146
ABSTRACT:   Thalassaemia is a heterogenerous group of disorders with a genetically determined reduction in the rate of synthesis of one or more types of normal haemoglobin polypeptide chain.A total of 308 cord blood samples from North Okkalapa General Hospital were screened for the presence of thalassaemia and haemoglobinopathies. The tests included haemoglobin electrophoresis, Hb A2 estimation, and H inclusionbodiesexamination.Hb F alone band was found in 256 cases (83.12%), Hb EF band revealed in 25 cases (8.12%), Hb FH band was seen in 23 cases (7.47%) and Hb EFH band revealed in 4 cases (1.3%). Haemoglobin H was seen in 27 cases (8.77%) in Hb FH and Hb EFH bands. Among them, 21 cases had Hb H inclusion percent < 10% of RBC and 3 cases had Hb H inclusion percent > 30%. Twenty-four cases showed Hb A2< 2%.According to this study, on cord blood electrophoresis, α-thalassaemia prevalence is comparable to those previously reported (10%).
SUBJECT HEADINGS:   alpha-Thalassemia. Fetal Blood.
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