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This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

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Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2007

Myanmar   Health   Sciences   Research   Journal

Volume   19,  Number   1

TITLE:   Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission.
AUTHOR:   Khin Saw Aye; Yin Thet Nu Oo; Kyaw Kyaw; Masanori Matsuoka
SOURCE:   Myanmar Health Sciences Research Journal. 2007; 19(1): 6-12
ABSTRACT:   The polymorphism of TTC repeats in Mycobacterium leprae was examined using bacilli from skin slit of leprosy patients attending at Central Special Skin Clinic, YGH and nasal swabs of their contacts to elucidate the possible mode of leprosy transmission. It was found that bacilli with different TTC genotypes were distributed among same household contacts and also harbored bacilli in patients were different TTC genotype from that harbored by the contacts. Genotypes of TTC repeats were found to differ between husband under treatment and his wife and also mother under treatment and her sons living in same house. These results revealed the possibility that in addition to exposure via the presence of a leprosy patient with a multibacillary (MB) infection who was living with family members, there might have been some infectious sources to which the residents had been commonly exposed outside the dwellings. A limited discriminative capacity of the TTC polymorphism in the epidemiological analysis implies the need of searching other useful polymorphic loci for detailed subdivision of clinical isolates. It was found that TTC genotype of bacilli harbored by household contacts was different with the TTC genotype by index cases. It was seen in the resident where TTC genotype was different in husband (index case) and his wife (HC) and the mother (index case) and her sons (HC). These results revealed that whether the family members get transmission either from their MB index cases or from outside the dwellings.
SUBJECT HEADINGS:   Genotype. Mycobacterium leprae. Polymorphism (Genetics).
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