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Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

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Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2008

Myanmar   Health   Sciences   Research   Journal

Volume   20,  Number   3

TITLE:   Experimental study on hypoglycemic activity of ethanolic extract of Andrographis paniculata Nees. on rats.
AUTHOR:   Tin Tin Thein; Maung Maung; Khin PhyuPhyu; Hein Myo Htet; Swe Swe; Myint Myint Khaing; Mee Mee Lwin
SOURCE:   Myanmar Health Sciences Research Journal. 2008; 20(3): 141-146
ABSTRACT:   The ethanolic extract of the whole plant of Andrographis paniculata (ေဆးခါး -ကီး/ငရုတfခါး) was tested for its acute hypoglycemic activity in adrenaline-induced hyperglycemic rats. It was examined after single oral administration of tested drug with the dosage of 400 mg/kg and 300 mg/kg body weight, standard drug (Glibenclamide) 0.5 mg/kg and distilled water 4ml/kg on rats which were seven numbers in each group. High dose of tested drug was as effective as standard drug in 4 consecutive hours after drugs administration (p>0.5). Low dose of tested drug had no significant difference with standard drug at 2, 3 & 4 hours (p>0.5) after the drug administration. The result revealed that A. paniculata in high dose was as effective as Glibenclamide whereas low dose of A. paniculata had less effectiveness at first hour. This study clearly indicated that an ethanolic extract of a whole plant of A. paniculatahas a significant acute hypoglycemic activity and gave scientific support in traditional usage of this plant.
SUBJECT HEADINGS:   Hypoglycemic Agents. Plant Extracts. Plants, Medicinal.
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