- To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
- To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
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Archives 2008
Myanmar Health Sciences Research Journal
Volume 20, Number 2
TITLE: Syndromic versus laboratory-based diagnosis for lower genital tract infections among married women in selected sub-urban communities, Yangon.
AUTHOR: Thein Myint Thu; Wah Wah Aung; Thaw Htet; Kyaw Min Htike; Wai Phyo; Thuzar Myint; Aye Aye Maw; Mi Mi Htwe
SOURCE: Myanmar Health Sciences Research Journal. 2008; 20(2): 101-106
ABSTRACT: The syndromic diagnosis is the most realistic and cost-effective strategy for controlling sexually transmitted infections (STI) in the developing countries. This approach relies on symptom recognition by an infected person who as a consequence seeks medical care. A cross-sectional study was carried out in January and April 2007 at Indaing and Hmawbi areas to determine the pre-valence of certain reproductive tract infections (gonorrhoea, trichomoniasis, candidiasis and bacterial vaginosis) and to evaluate the accuracy of the syndromic diagnosis by comparing with laboratory diagnosis. Of 212 sympto-matic and asymptomatic married women (93 from Indaing and 119 from Hmawbi), the prevalence of gonorrhoea was 3.8%, trichomoniasis 17.5%, candidiasis 15.6% and of bacterial vaginosis 13.2%. Syndromic diagnosis for lower genital tract infections (LGTI) was made on the basis of presence of clinical symptom of vaginal discharge and signs such as creamy white or greenish-yellow vaginal discharge and/or vaginitis and/or cervicitis on speculum examination. Among 80 laboratory-confirmed LGTI (trichomo-niasis, candidiasis and bacterial vaginosis), syndromic diagnosis can detect 47.5% (38/80) of these infections. There is unsatisfactory agreement between laboratory diagnosis and syndromic diagnosis (Kappa coefficient= 0.04). The present study found out the occurrence of asymptomatic reproductive tract infection in the community and clinical judgement based on symptoms and signs seemed to be less indicative for LGTI. The lack of association between symptoms and laboratory-confirmed infections underscores the challenge of diagnosing LGTI when laboratory testing is not available.
SUBJECT HEADINGS: Spouses. Adnexitis.
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