Original Articles 2012-02-20

The Use of Herbal Medicine and Traditional Medicine Formulations (TMFs) for Hypertension at Traditional Medicine Hospital, Yangon

This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

Original Articles 2020-09-11

Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

Original Articles 2020-09-14

Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

Next Prev

Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2008

Myanmar   Health   Sciences   Research   Journal

Volume   20,  Number   1

TITLE:   Preparation and standardization of an antimalarial phytopharmaceutical product from Swertia purpurescens (Pan Kha).
AUTHOR:   Khin PhyuPhyu; Win Myint; Aye Than; Thein Tun; Ye Htut; Myint Sein; Tin Tin Thein; Lei Lei Win; Saw Ohnmar Khin
SOURCE:   Myanmar Health Sciences Research Journal. 2008; 20(1): 46-50
ABSTRACT:   A standardized phytomedicine is locally produced from Pan Kha, Swertia purpurescens. Its antimalarial activity and the active principle were approved in 2004. The plant material was extracted with three different concentrations of ethanol; 50%, 70% and 96%. The 96% ethanol extract showed the presence of large amount of flavonoid (xanthone). This herbal drug was physicochemically and phytochemically standardized by using chromatographic and phytochemical methods for its herbal pharmacopoeial quality criteria. This phytomedicine was found to contain 7.82 mg% active principle, bellidifolin by HPLC analysis. The median lethal dose (LD50) was determined as 37 (27.40-49.95) g/kg. Sub-acute toxicity test showed that there was no decrease in body weight of albino rats. No significant changes in weight of the internal organs, the biochemical and haema-tological profiles of the test groups were observed when compared with the control group. These findings call for a clinical trial of this medicine to be tested on human being.
SUBJECT HEADINGS:   Antimalarials. Pharmaceutical Preparations. Plants, Medicinal.
FULL TEXT: