Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2008

Myanmar   Health   Sciences   Research   Journal

Volume   20,  Number   1

TITLE:   Perinatal transmission of Group B Streptococcal infection.
AUTHOR:   Cho Cho Thet; Moe Moe Tun; Thein Tun; Khin Lin; Maung Maung; Mar Lar Win; Aye Aye Hlaing; Kyi Kyi Myint
SOURCE:   Myanmar Health Sciences Research Journal. 2008; 20(1): 27-32
ABSTRACT:   Group B Streptococcus (GBS) is a leading cause of invasive bacterial infection in newborns and also affects pregnant women. The objective of this study was to determine the vertical transmission of GBS infection from mothers to fetus. It was hospital-based cross-sectional descriptive study. One hundred and fifty pairs of pregnant women and their neonates were studied in Mandalay 300 bedded hospital between May, 2006 and April, 2007. Swabs from both vagina and rectum from mothers and ear, nose and umbilicus from neonates were collected and cultured on selective media. Risk factors were investigated by chart review and hygienic status of mothers was assessed by investigators. The overall maternal GBS colonization rate was 16% and perinatal transmission rate was 75%(n =18/24). Significant vertical transmission was observed from colonized mothers to their infants (OR = 91.5) (p < 0.001). The association between maternal GBS colonization and maternal conditions such as prolong labour, fever and premature rupture of membrane (PROM) was observed. Erythromycin and tetracycline were the most sensitive drugs on GBS.Ampicillin was effective in vaginal site colonization only. Penicillin was effective in ear colonization of the neonates only. This finding would be helpful to health-care providers in management of GBS infection among mothers and infants.
SUBJECT HEADINGS:   Perinatal Care. Disease Transmission, Vertical. Streptococcal Infections.
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar