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This study was done to determine the use of herbal medicines and Traditional Medicine Formulations (TMFs) for treating hypertension at Outpatients' Department (OPD) of Traditional Medicine Hospital, Yangon. This study was a cross-sectional, descriptive study in 140 hypertensive patients attending th

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Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

To tackle the maternal, newborn and child health (MNCH) care needs is a challenging situation in remote and hard-to-reach areas. Intervention activities focusing on strengthening community health care network through community participation and supporting Basic Health Staffs for MNCH ser

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Incidence of Snakebite in Four Townships of Yangon Region

The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2009

Myanmar   Health   Sciences   Research   Journal

Volume   21,  Number   2

TITLE:   Efficacy and safety of artemisinin-piperaquine (Artequick) compared to dihydroarte-misinin-piperaquine (Artekin) in uncomplicated falciparum malaria in adults.
AUTHOR:   Khin Phyu Phyu; Win Win Myint; Myar Phone Kyaw; Thaw Zin; Marlar Than
SOURCE:   Myanmar Health Sciences Research Journal. 2009; 21(2): 78-82
ABSTRACT:   A hospital-based, randomized controlled study was done at No. 1 MH (1000 Bedded), Mingaladon, No. 1 MH (700 Bedded), PyinOoLwin and No. 9 MH (100 Bedded), Lashio, on a total of 64 uncomplicated falciparum malaria patients from January to September 2007, to determine the therapeutic efficacy, safety and tolerability of artemisinin-piperaquine (Artequick) tablet in comparison with dihydroartemisinin-piperaquine (Artekin) for the treat-ment of 30 uncomplicated falciparum malaria patients in adults. Artequick 2 tabs was given at 0 and 24 hours in one group and Artekin 2 tabs was given at 0, 6, 24 and 32 hours in the control group. Initial parasitaemia/µl were 16471.88±38755.1 and 13528.9±1909.3. Fever clearance times (FCT) were 43.23±17.35 and 12.4±13.1 hours, and Parasite clearance times (PCT) were 57.6±21.88 and 46.8±22.1 hours, respectively, in Artequick and Artekin groups. In Artequick group, there were four late treatment failures (LTF) that adequate clinical and parasitological response (ACPR) was 94% compared to 100% ACPR in Artekin group. There were no serious side effects. Artequick is as safe as Artekin but with lower ACPR in this study. Further dose finding studies will be needed to establish its efficacy in the treatment of uncomplicated falciparum malaria in adults.
SUBJECT HEADINGS:   Malaria, Falciparum. Antimalarials.
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