Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2009

Myanmar   Health   Sciences   Research   Journal

Volume   21,  Number   1

TITLE:   A clinicopathological study of myelodysplastic syndromes in YGH
AUTHOR:   Min Min Win; Myint Myint Hla; Aye Aye Myint; Khine San Yin
SOURCE:   Myanmar Health Sciences Research Journal. 2009; 21(1):62-64
ABSTRACT:   The clinical and haematological studies of 36 cases of myelodysplastic syndromes (MDS), none of which had previously received chemotherapy or radiotherapy were studied. They were classified according to FAB classification. There were 19 males and 17 females in age ranging from 22 to 87 years. Among them, there were 24 cases of refractory anemia (RA), 4 cases in each of refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-t)and chronic myelomonocytic leukaemia (CMML). Symptoms of anemia were present n 97.2%, infective manifestations in 55.6%, bleeding manifestations in 38.9%, hepatomegaly in 11.2%, splenomegaly in 8.4% and lymph-adenopathy in 5.6% of patients. Haematological findings showed that pancytopenia in 61.1%, combination of anemia and thrombocytopenia in 22.2%, combination of anemia and leucopenia in 11.1% and anemia only in 5.6% of MDS patients.In the bone marrow examination, hypercellularity in 27 cases, hypocellularity in 9 cases and dyshaemopoiesis involving two or more cell lines were seen in all cases.
SUBJECT HEADINGS:   Myelodysplastic Syndromes
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar