Myanmar Health Sciences Research Journal
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Aims of MHSR Journal
  • To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
  • To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
  • To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development


Archives   2009

Myanmar   Health   Sciences   Research   Journal

Volume   21,  Number   1

TITLE:   Determination of dengue antibody among the children admitted to Mandalay Children Hospital.
AUTHOR:   Yee Yee Lwin; Sandar Lin; Yin Yin Khaing; Thindar Maw; Kay Thi Aye; Pe Thet Khin; Tin Myint; Khin Htwe; Kyaw Zin Thant
SOURCE:   Myanmar Health Sciences Research Journal. 2009; 21(1): 32-37
ABSTRACT:   Myanmar belongs to the disease endemic countries (DEC) of dengue virus infection. In order to explore the dengue antibody status among the children, a hospital-based study was first introduced in Mandalay in the years 2006 and 2007 by the Virology Research Division, Department of Medical Research (Upper Myanmar) jointly with the Mandalay Children Hospital.Blood samples were collected from the patients who gave informed consent, and were sent to the Department of Medical Research (Upper Myanmar) for the virological studies.A total of 570 blood samples were obtained during dengue seasons of two consecutive years (from May 2006 to August 2007) from 484 clinically-diagnosed cases of dengue haemorrhagic fever (DHF), comprising 484 acute phase samples (S1) and 86 convalescent phase samples (S2).Paired sera were obtained from 86 patients (17.7% of patients from whom S1 was taken).A panel of samples (182 in number) was tested by PanBio Dengue Duo IgM and IgG ELISA tests.Among the tested samples, 153 samples showed positive result for dengue antibody (either IgM alone or both IgM and IgG) which in turn indicated 84% laboratory- confirmed cases of dengue infection.This study also paves the way to explore more about the seroepidemiology and molecular epidemiology of dengue viruses circulating in Mandalay and Upper Myanmar.
SUBJECT HEADINGS:   Dengue. Antibodies.
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar