- To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
- To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
- To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development
Archives 2009
Myanmar Health Sciences Research Journal
Volume 21, Number 1
TITLE: Anti-inflammatory and anti-plaque activity of Ponna yeik (Ixora coccinea Linn.) leaves extract used as mouthwash on chronic gingivitis patients.
AUTHOR: May Aye Than; Moe Wint Oo; Tin Htun Hla; Aye Than; Thein Tut; May Thet Lwin
SOURCE: Myanmar Health Sciences Research Journal. 2009; 21(1): 26-31
ABSTRACT: Ponna yeik ( Ixora coccinea Linn.) islocally claimed to be useful in treatment of toothache and oral diseases as a mouthwash in Myanmar. In Myanmar, 80% of school children had gingivitis and 18% of them had periodontal destruction. Bacterial plague in oral cavity is regarded as the primary local etiological factor in inflammatory disease. Preventing and controlling of periodontal disease would prevent the microbial colonization of plague on the teeth and gingiva. There are varieties of antiseptic mouthwashes in modern dental practice, but chlorhexidine gluconate is the most effective anti-plague mouthwash, which is not cheap and easily available. This study with the aim to evaluate the efficacy of Ponna yeik mouthwash, which was easily available at low cost, was conducted at the Institute of Dental Medicine, Yangon. The study design was a randomized controlled clinical trial and chlorhexidine gluconate was used as a positive standard drug. Twenty patients with typical chronic gingivitis who participated in this study were randomly divided into two groups, 10 patients for 0.2% watery extract of Ponna yeik mouthwash and 10 patients for 0.2% chlorhexidine mouthwash two times a day for 4 weeks. The plaque score, bleeding on probing supra-gingival plaque formation, staining effect and severity of gingivitis were examined prior to the clinical trial, as baseline and 4 weeks after trial. Both chlorhexidine and Ponna yeik mouthwashes showed significant effectiveness in plague score, bleeding on probing and severity of gingivitis when compared to before treatment. Staining effects were observed in patients who used chlorhexidine but not in patients who used Ponna yeik mouthwash. There were no significant differences between two groups in all scores except staining score after 4 weeks of treatment. It was concluded that Ponna yeik mouthwash revealed anti-inflammation and anti-plague activity without staining.
SUBJECT HEADINGS: Anti-Inflammatory Agents. Medicine, Traditional. Plants, Medicinal. Dental Plaque. Plant Extracts. Mouthwashes. Gingivitis.
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