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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2009

Myanmar   Health   Sciences   Research   Journal

Volume   21,  Number   1

TITLE:   Acute effect of onion (Allium cepa) on blood glucose level of diabetic patients.
AUTHOR:   Zaw Myint; Hnin Lwin Htun; Theingi Thwin; Thet Thet Mar; Mie Mie Nwe; Aye Myint Oo; Lwin Zar Maw; Tin Ko Ko Oo; May Thu Kyaw
SOURCE:   Myanmar Health Sciences Research Journal. 2009; 21(1): 22-25
ABSTRACT:   To determine the acute effect of onion on blood glucose levels of diabetic (NIDDM) patients, a self-controlled study was done. It included 20 diabetic patients whose fasting plasma glucose concentration exceeded 126 mg/dl. After taking the fasting plasma glucose sample, 50 g of oral glucose load was given to the patients and the plasma glucose levels at thirty-minute time intervals up to two hours were taken again (OGTT). Then, the same procedure was done after one week at which glucose load and onion (50 g) were administered.The results were analyzed by using paired ‘t’ test. The mean fasting plasma glucose concentrations of diabetic patients were 147.3517.18 mg/dl vs 149.619.76 mg/dl, (p=0.199), respectively. When the glucose and onion were administered, the plasma glucose levels were found to be decreased when compared to those levels after giving glucose only; (225.6027.25 mg/dl vs 214.4033.39 mg/dl at 30 min; p=0.099), (282.5531.67 mg/dl vs 229.4037.61 mg/dl at 60 min; p=0.0001), (270.2022.48 mg/dl vs 194.4537.26 mg/dl at 90 min; p=0.0001) and (248.7520.13 mg/dl vs 161.6530.50 mg/dl at 120 min; p=0.0001), respectively. This study shows that onion has an acute effect of lowering the plasma glucose levels which could be useful in the management of patients with diabetes mellitus.
SUBJECT HEADINGS:   Medicine, Traditional. Plants, Medicinal. Blood Glucose. Onions. Diabetes Mellitus.
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