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Is Community Intervention Effective for Improving Maternal, Newborn and Child Health Care in Hard-to-Reach Areas of Chin State, Myanmar?

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The true incidence of snakebite in Myanmar is unknown. The current data are based on hospital returns to Ministry of Health and Sports and they are likely to be under-reported. A community-based survey is useful to know the current burden of snakebite and thus for planning and formulating str

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Aims of MHSR Journal

• To serve as an important medium for the publication of original research in the field of medical science and health research, thus filling gaps in health knowledge for effective utilization of research findings
• To impart current medical knowledge and updated scientific information obtained from research to health professionals for better and appropriate health care management
• To disseminate recent basic, applied and social research findings among health personnel of different strata for enhancing worldwide health development

Archives   2009

Myanmar   Health   Sciences   Research   Journal

Volume   21,  Number   1

TITLE:   Serological response of chemoprophylaxis on high risk contacts of new leprosy cases in Nyaungdon Township.
AUTHOR:   Khaing Win Htun; Khin Nwe Oo
SOURCE:   Myanmar Health Sciences Research Journal. 2009; 21(1): 7-11
ABSTRACT:   This study was carried out in one of the leprosy endemic townships, Nyaungdon Township, Ayeyawady Division. The aim was to study the serological response of chemoprophylaxis by using a single dose of ROM (rifampicin, ofloxacin and minocycline), which is WHO recommended regime for single lesion of leprosy, on high risk extended contacts of new leprosy cases. The blood samples were collected from extended contacts two times before and six months after the chemoprophylaxis. Indirect NTP-BSA ELISA test was carried out on samples. Determination of the baseline seropositivity rate of extended contacts of new leprosy case was also carried out. Seropositive contacts were assumed as high risk group. In the baseline study, the seropositivity rate is significantly higher in household contacts of multibacillary (MB) leprosy cases. The seropositivity rate ofchildren contacts under 15 years of age is higher than that of adult contacts, 2= 31.58, p<0.001.The difference of mean OD titers in treated group before and after chemoprophylaxis is significantly reduced compared to non-treated group in adult, p=0.004. However, it is not significant in children. The difference of seropositivity rate before and six months after chemoprophylaxis is not significantly reduced in treated group compared to non-treated group.
SUBJECT HEADINGS:   Chemoprevention. Leprosy.
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