Combined Effect of Upanaha Sweda with Traditional Medicine Formulation-43 (Akin: Hse Pa: Hsei:) and Polyherbal Medicated Oil on Patients with Janu Sandhigata Vata

Khaing Mar Myint*, Khaing Myo, Than Than Htwe, Maung Maung Thet & Win Soe

Myanmar Health Sciences Research Journal, Vol. 37, No. 1-3, 2025

Traditional Medicine Formulation-43 (TMF-43) (Akin: Hse Pa: Hsei:) is one of the most effective drugs for Janu Sandhigata Vata. Polyherbal medicated oil is effective in the elimination of vitiated vayu, reducing pain in movement and swelling. This combination of TMF-43 and polyherbal medicated oil is commonly used for the treatment of patients with Janu Sandhigata Vata at Traditional Medicine Hospitals and Clinics. However, there is no scientific research done on the combined effect of TMF-43 and polyherbal medicated oil. The patients who fulfilled the inclusion criteria from IPD and OPD at 100 Bedded Traditional Medicine Teaching Hospital (TMTH), Mandalay after obtaining informed consent were selected and a total of 22 patients were included in this study. The study design was before and after interventional study and carried out from March 2020 to October 2022. The participants were given treatment for 7 consecutive days and they took a rest on every 8^th day. 

Sandhigata Vata can be defined as a disease of sandhi with symptoms of sandhi shoola (joint pain) and sandhi shotha (inflammation in knee joints), etc. Janu Sandhigata Vata: Janu refers to knee, Sandhi is joint and Vata is the air element permeating the knee joint. With advancing age, the influence of Vata Dosha increases, resulting in the gradual degeneration of the body.¹ Janu Sandhigata Vata is an Ayurvedic term and it is a common Vata disorder described under Vata Vyadhi in Ayurveda. 

Study Design

Before and after interventional study

Study Site

Outpatient Department and Inpatient Department of 100 Bedded Traditional Medicine Teaching Hospital (TMTH), Mandalay

Study Period

March 2020 to October 2022.

Study Population

The patients were selected according to the signs and symptoms who were diagnosed as Janu Sandhigata Vata during study period.

Sample Size

The required sample size was 22 patients.⁷

A total of 22 patients with Janu Sandhigata Vata from IPD and OPD of TMTH, Mandalay were included. All patients were treated with Upanaha Sweda (external application with TMF-43 (Akin: Hse Pa: Hsei:) and Polyherbal medicated oil followed by bandaging) therapy. Patients were evaluated before treatment (Day 0), at the end of 1^st course (Day 8) and at the end of 2^nd course (Day 16) of the treatment. The outcome measures were assessment of pain at rest, pain on standing, the duration of morning stiffness, tenderness, swelling, crepitus and flexion (ROM).

We would like to express our deepest gratitude to all members of Postgraduate Board of Studies, University of Traditional Medicine for permission and suggestions and, members of Implementation Research Committee, Ministry of Health for their support grant. Moreover, we are thankful to all who helped us directly and indirectly for our research work.

The authors declare that they have no competing interests.

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