Myanmar Health Sciences Research Journal
Original Articles :
Myanamr Health Research Registration 2023; 35(1-3): 27-33.
DOI:

Acute Toxicity and Antipyretic Activity of Traditional Medicine Formulation (TMF-76) Apu-Kja-Hsei on Animal Models

Myint Myint Kyi, Hla Myo Win, Khine Khine Lwin, Myo Thidar Aye, Myint Myint Khine, Mi Mi Thaw, Khin Taryar Myint and Than Tun

Myanmar Health Sciences Research Journal, 2023; 35(1-3):27-33

ABSTRACT

Traditional Medicine Formulation-76 (TMF-76) (Apu-Kja-Hsei:) is a special antipyretic drug with herbomineral preparation of 4 kinds of ingredients which is useful in the treatment of pyrexia. This study was performed to evaluate the acute toxicity and antipyretic activity of
TMF-76 on animal models.


RESULT
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INTRODUCTION
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Body heat is generated by basal metabolic activity and muscle movement, and lost by conduction, convection, evaporation and radiation. Body temperature is controlled in the hypothalamus, which is directly sensitive to changes in core temperature and indirectly responds to temperature-sensitive neurons in the skin.


SUPPLEMENTARY MATERIAL
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Study design was laboratory based experimental animal study. Study site was Research Division, University of Traditional Medicine (Mandalay) and Pharmacology Research Division, Department of Medical Research (Yangon).


DISCUSSION
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Traditional medicine is the medical system based on the concept of Mahabhuta. According to Myanmar traditional medicine, almost all of the fever is due to excessive of ushna tejo in body.


ACKNOWLEDGMENT
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CONFLICT OF INTEREST
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REFERENCES
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